Related: BCMB 412 Advanced Molecular Biology and Genomics
ATTENTION
ribozymes = rnases
Ribozymes are RNA molecules that can catalyze specific biochemical reactions, like RNA splicing and gene expression, similar to the typical protein enzyme. The most common thing they do is cleave.
example of ribonuclease P
ribonuclease P (RNase P) is a holoenzyme (complete, functional enzyme that’s catalytically active) that requires a coenzyme to become active. RNase P targets the 5’ ends of precursor tRNAs and cleaves them to produce mature tRNAs.
RNases are horrible for single-cell sequencing library preparation